Anti-ARHGAP8 Aptamer(Cat#: CTApt-1212)
This product is an aptamer which binds to the ARHGAP8 with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ARHGAP8 |
| Alternative Names |
Rho GTPase Activating Protein 8; Rho-Type GTPase-Activating Protein 8; Rho GTPase-Activating Protein 8; BPGAP1; BNIP-2 And Cdc42GAP Homology Domain-Containing, Proline-Rich And Cdc42GAP-Like Protein Subtype-1; BCH Domain-Containing Cdc42GAP-Like Protein; FLJ20185; ARHGAP8; PP610 |
| Gene ID |
23779 |
| UniProt ID |
P85298 |
| Target Overview |
This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
